Publications

40. P. Chai, Q. Rao, K. Zhang#, Multi-curve fitting and tubulin-lattice signal removal for structure determination of large microtubule-based motors. J Struct Biol, 2022: p. 107897.

39. L. Han*, Q. Rao*, R. Yang*, Y. Wang*, P. Chai*, Y. Xiong, and K. Zhang#, Cryo-EM structure of an active central apparatus. Nat Struct Mol Biol, 2022. 29(5): p. 472-482.

38. P. Chai, Y. Wang, L. Han, Q. Rao, R. Yang, K. Zhang# (2022). Structural analysis of dyneins by cryo-electron microscopy. (Methods in Molecular Biology, invited book chapter).

37. Jiao Li*, Long Han*, Francesca Vallese*, Ziqiao Ding, Sylvia K. Choi, Sangjin Hong, Yanmei Luo, Bin Liu, Jiapeng Zhu#, Oliver Clarke#, Kai Zhang#, Robert Gennis#. (2021). Cryo-EM structures of E. coli cytochrome bo3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. PNAS, 118(34), e2106750118.

36. Q. Rao*, L. Han*, Y. Wang*, P. Chai*, Y. W. Kuo, R. Yang, F. Hu, Y. Yang, J. Howard, and K. Zhang#, Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism. Nat Struct Mol Biol, 2021. 28(10): p. 799-810. (Ian and Barbara Gibbons Award)

35. F. Leng, H. Yin, S. Qin, K. Zhang, Y. Guan, R. Fang, H. Wang, G. Li, Z. Jiang, F. Sun, D. C. Wang, and C. Xie, NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation. Sci Rep, 2020. 10(1): p. 198.

34. Y. Hu, B.A. Desimmie, H.C. Nguyen, S.J. Ziegler, T.C. Cheng, J. Chen, J. Wang, H. Wang, K. Zhang, K. Pathak#, Y. Xiong#. (2019). Structural basis of antagonism of human APOBEC3F by HIV-1 Vif. Nat. Struct. Mol. Biol. 26, 1176-1183.

33. J. Ma, Y. Zhai, M. Chen, K. Zhang, Q. Chen, X. Pang, and F. Sun (2019). New interfaces on MiD51 for Drp1 recruitment and regulation. PloS one 14, e0211459.

32. K. Zhang# (2018) "Towards dynamic structure of biological complexes at atomic resolution by cryo-EM ", Chin. Phys. B. 27(6): 066801 (invited)

31. K. Zhang#, and Z. Liu# (2018). "A brief introduction of cryo-EM revolution-the Nobel Prize in Chemistry 2017." Science China. 61(3): 368-370. (invited)

30. K. Zhang*, H.E. Foster*, A. Rondelet, S.E. Lacey, N. Bahi-Buisson, A.W. Bird, A.P. Carter (2017). “Cryo-EM reveals how human cytoplasmic dynein is auto-inhibited and activated”, Cell. 169: 1303–1314.

29. G. Lu, Y. Xu, K. Zhang, Y. Xiong, H. Li, L. Cui, X. Wang, J. Lou, Y. Zhai, F. Sun, and X.C. Zhang (2017). "Crystal structure of E. coli Apolipoprotein N-acyl Transferase", Nat. Commun. 8: 15948.

28. K. Zhang# (2016)."Gctf: Real-time CTF determination and correction", J. Struct. Biol. 93(1):1–12.

27. Y. Chen*, Y. Zhang*, K. Zhang*#, Y. Deng, F. Zhang#, F. Sun# (2016). “FIRT: filtered iterative reconstruction technique with information restoration”, J. Struct. Biol. 195(1):49-61.

26. L. Umavicius*, K. Zhang*, A.G. Diamant*, C. Motz, M.A. Schlager, M. Yu, N.A. Patel, C.V. Robinson, A.P. Carter (2015). "The structure of the dynactin complex and its interaction with dynein." Science. 347 (6229): 1441-1446 (Cover Story)

25. X. Pang, J. Fan, Y. Zhang, K. Zhang, B. Gao, J. Ma, J. Li, Y. Deng, Q. Zhou, E. H. Egelman, V. W. Hsu and F. Sun (2014). "A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature." Dev. Cell. 31(1): 73-86.

24. B. Qiu, K. Zhang, S. Wang and F. Sun (2014), "C-terminal motif within Sec7 domain regulates guanine nucleotide exchange activity via tuning protein conformation." BBRC, 446(1): 380-386.

23. L. Cheng, X. Huang, X. Li, W. Xiong, W. Sun, C. Yang, K. Zhang, Y. Wang, H. Liu, X. Huang, G. Ji, F. Sun, C. Zheng and P. Zhu (2014). "Cryo-EM structures of two bovine adenovirus type 3 intermediates." Virology 450-451: 174-181.

22. Y. Zhang, W. Wang, J. Chen, K. Zhang, F. Gao, B. Gao, S. Zhang, M. Dong, F. Besenbacher, W. Gong, M. Zhang, F. Sun and W. Feng (2013). "Structural insights into the intrinsic self-assembly of Par-3 N-terminal domain." Structure. 21(6): 997-1006.

21. K. Zhang, L. Wang, Y. Liu, K. Y. Chan, X. Pang, K. Schulten, Z. Dong and F. Sun (2013). "Flexible interwoven termini determine the thermal stability of thermosomes." Protein Cell. 4(6): 432-444. (Cover Story)

20. H. Wang, K. Zhang, J. Zhu, W. Song, L. Zhao and X. Zhang (2013). "Structure reveals regulatory mechanisms of a MaoC-like hydratase from Phytophthora capsici involved in biosynthesis of polyhydroxyalkanoates (PHAs)." PLoS One. 8(11): e80024.

19. X. Wang, F. Xu, J. Liu, B. Gao, Y. Liu, Y. Zhai, J. Ma, K. Zhang^, T.S. Baker, K. Schulten, D. Zheng, H. Pang, and F. Sun (2013), "Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography." PLoS Pathog, 9(1): p. e1003132.

18. L. Wang, Q. Li, L. Wu, S. Liu, Y. Zhang, X. Yang, P. Zhu, H. Zhang, K. Zhang, J. Lou, P. Liu, L. Tong, F. Sun, and Z. Fan (2013), "Identification of SERPINB1 as a physiological inhibitor of human granzyme H." J. Immunol., 190(3): p. 1319-30.

17. G. Zhang, X. Lu, B. Shen, K. Zhang, Q. Chu, and K. Zhao (2012). "Design and Optimization of Simultaneous Iterative Reconstruction Technique Based on GPU Platform." Computer Science, 39: 310-313.

16. L. Wang, K. Zhang, L. Wu, S. Liu, H. Zhang, Q. Zhou, L. Tong, F. Sun, and Z. Fan (2012), "Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif." J. Immunol., 188(2): p. 765-73.

15. M. Bai, X. Pang, J. Lou, Q. Zhou, K. Zhang, J. Ma, J. Li, F. Sun, V. Hsu (2012), "Mechanistic insights into regulated cargo binding by ACAP1". J. Biol. Chem., 287: 28675-28685.

14. C. Yang, G. Ji, H. Liu, K. Zhang, G. Liu, F. Sun, P. Zhu, L. Cheng (2012), "Cryo-EM structure of a transcribing cypovirus." PNAS, 109(16): 6118-6123.

13. X. Wan, F. Zhang, Q. Chu, K. Zhang, F. Sun, B. Yuan, Z. Liu (2011), "Three-dimensional reconstruction using an adaptive simultaneous algebraic reconstruction technique in electron tomography." J. Struct. Biol., 175(3):277-87.

12. X. Zheng, J. Guo, L. Xu, H. Li, D. Zhang, K. Zhang, F. Sun, T. Wen, S. Liu, H. Pang (2011), "Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis." PLoS ONE, 6(5): e20506.

11. Q. Chu, K. Zhang^, X. Wan, C. Zhang, G. Zhang, B. Shen, X. Liu, K. Zhao, X. Chu, F. Zhang and F. Sun (2011). "ATOM 1.0: A GPU Powered Package for Electron Tomography Reconstruction." Acta Biophys. Sin. 27(3):231-241. (^initiated the project)

10. Y. Zhai, K. Zhang*, Y. Huo*, Y. Zhu, Q. Zhou, J. Lu, I. Black, X. Pang, A. W. Roszak, X. Zhang, N. W. Isaacs and F. Sun (2011). "Autotransporter passenger domain secretion requires a hydrophobic cavity at the extracellular entrance of the β-domain pore." Biochem. J. 435:577-587.

9. L. Cheng*, J. Sun*, K. Zhang, Z. Mou, X. Huang, G. Ji, F. Sun, J. Zhang and P. Zhu (2011). "Atomic model of a cypovirus built from cryo-EM structure provides insight into the mechanism of mRNA capping." PNAS. 108(4): 1373-1378.

8. L. Wang, K. Zhang, Z. Fan, Z. Dong and F. Sun (2011). "Substrate Binding Properties of Thermosome ATcpn-β from Acidianus Tengchongensis." PIBB. 38(2): 151-158.

7. Q. Chu, F. Zhang, K. Zhang, X. Wan, M. Chen and Z. Liu (2010). "An accurate, automatic method for markerless alignment of electron tomographic images." BIBM2010

6. Y. Huo*, Z. Hu*, K. Zhang*, L. Wang, Y. Zhai, Q. Zhou, G. Lander, J. Zhu, Y. He, X. Pang, W. Xu, M. Bartlam, Z. Dong and F. Sun (2010). "Crystal structure of group II chaperonin in the open state." Structure 18(10): 1270-1279. (Cover)

5. K. Zhang, Y. Zhang, Z. Hu, J. Gang and F. Sun (2010). "Development and Frontier of Electron Microscopy 3D Reconstruction." Acta Biophys. Sin. 26(7): 209-215. (Cover)

4. S. Zhang, K. Zhang, X. Chen, X. Chu, F. Sun and Z. Dong (2010). "Five mutations in N-terminus confer thermostability on mesophilic xylanase." BBRC. 395(2): 200-206.

3. Z. Li, K. Zhang, Y. Zhai, Q. Zhou, Y. Geng and F. Sun (2010). "Cloning, Expression, Purification and Preliminary Crystallographic Analysis of Caenorhabditis elegans Enoyl-CoA Hydratase." Acta Biophys. Sin. 26(1): 37-48.

2. K. Zhang, C. Zhang and F. Sun (2009). "Disclosing the Structure and Function of Translation Machine: Introduction of the Nobel Prize in Chemistry 2009." Acta Biophys. Sin. 25(5):325-334.

1. S. Sun*, K. Zhang*, W. Xu, G. Wang, J. Chen and F. Sun (2009). "3D Structural Investigation of Caveolae from Porcine Aorta Endothelial Cell by Electron Tomography." PIBB. 36(6): 729-735.